Glucose Dysregulation Interacts With APOE-∊4 to Potentiate Temporoparietal Cortical Thinning
نویسندگان
چکیده
منابع مشابه
Longitudinal changes in medial temporal cortical thickness in normal subjects with the APOE-4 polymorphism
People with the apolipoprotein-Eepsilon4 (APOE-4) genetic risk for Alzheimer's disease show morphologic differences in medial temporal lobe regions when compared to non-carriers of the allele. Using a high-resolution MRI and cortical unfolding approach, our aim was to determine the rate of cortical thinning among medial temporal lobe subregions over the course of 2 years. We hypothesized that A...
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Does accelerated cortical atrophy in aging, especially in areas vulnerable to early Alzheimer's disease (AD), unequivocally signify neurodegenerative disease or can it be part of normal aging? We addressed this in 3 ways. First, age trajectories of cortical thickness were delineated cross-sectionally (n = 1100) and longitudinally (n = 207). Second, effects of undetected AD on the age trajectori...
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ژورنال
عنوان ژورنال: American Journal of Alzheimer's Disease & Other Dementiasr
سال: 2015
ISSN: 1533-3175,1938-2731
DOI: 10.1177/1533317515587084